{"id":27307,"date":"2026-05-06T06:50:50","date_gmt":"2026-05-06T06:50:50","guid":{"rendered":"https:\/\/www.neuraxpharm.com\/it\/?page_id=27307"},"modified":"2026-05-06T06:54:10","modified_gmt":"2026-05-06T06:54:10","slug":"efficacia-provata","status":"publish","type":"page","link":"https:\/\/www.neuraxpharm.com\/it\/portafoglio\/sclerosi-multipla\/efficacia-provata\/","title":{"rendered":"Efficacia provata"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"27307\" class=\"elementor elementor-27307\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5f1bbbb elementor-section-height-min-height elementor-section-items-bottom elementor-section-boxed elementor-section-height-default\" data-id=\"5f1bbbb\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t\t<div class=\"elementor-background-overlay\"><\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7ce5ee3\" data-id=\"7ce5ee3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-78402b2 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"78402b2\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-cc42b85\" data-id=\"cc42b85\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-a51e718 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a51e718\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5c55bcb\" data-id=\"5c55bcb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ae30f60 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ae30f60\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-450c5a0\" data-id=\"450c5a0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ee2e9ea jet-breadcrumbs-align-left elementor-widget elementor-widget-jet-breadcrumbs\" data-id=\"ee2e9ea\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"jet-breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-jet-breadcrumbs jet-blocks\">\n\t\t<div class=\"jet-breadcrumbs\">\n\t\t<div class=\"jet-breadcrumbs__content\">\n\t\t<div class=\"jet-breadcrumbs__wrap\"><div class=\"jet-breadcrumbs__item\"><a href=\"https:\/\/www.neuraxpharm.com\/it\/\" class=\"jet-breadcrumbs__item-link is-home\" rel=\"home\" title=\"Home\">Home<\/a><\/div>\n\t\t<\/div>\n\t\t<\/div>\n\t\t<\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-37c22b2 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"37c22b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tBRIUMVI\u00ae is where efficacy meets efficiency for patients with relapsing MS\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-4f2a061 elementor-section-content-middle elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"4f2a061\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-3338960\" data-id=\"3338960\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2eb7396 elementor-widget elementor-widget-text-editor\" data-id=\"2eb7396\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Riduzione significativa delle ricadute (endpoint primario)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8fa35b2 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"8fa35b2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"#riduzione\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" id=\"Capa_2\" data-name=\"Capa 2\" viewBox=\"0 0 47.46 47.46\"><defs><style>      .cls-1 {        fill: #ffc72c;        stroke-width: 0px;      }    <\/style><\/defs><g id=\"PROVEN_EFFICACY\" data-name=\"PROVEN EFFICACY\"><g id=\"ICON_MORE\" data-name=\"ICON MORE\"><path class=\"cls-1\" d=\"M23.73,0C10.64,0,0,10.64,0,23.73s10.64,23.73,23.73,23.73,23.73-10.64,23.73-23.73S36.81,0,23.73,0ZM23.73,44.07c-11.21,0-20.34-9.12-20.34-20.34S12.51,3.39,23.73,3.39s20.34,9.12,20.34,20.34-9.12,20.34-20.34,20.34Z\"><\/path><path class=\"cls-1\" d=\"M33.33,22.03h-7.91v-7.91c0-.94-.76-1.69-1.69-1.69s-1.69.76-1.69,1.69v7.91h-7.91c-.94,0-1.69.76-1.69,1.69s.76,1.69,1.69,1.69h7.91v7.91c0,.94.76,1.69,1.69,1.69s1.69-.76,1.69-1.69v-7.91h7.91c.94,0,1.69-.76,1.69-1.69s-.76-1.69-1.69-1.69Z\"><\/path><\/g><\/g><\/svg>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-0bbf412\" data-id=\"0bbf412\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8f62a01 elementor-widget elementor-widget-text-editor\" data-id=\"8f62a01\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Soppressione quasi completa delle lesioni<br \/><br \/><br \/><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c29cdb7 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"c29cdb7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"#soppressione\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" id=\"Capa_2\" data-name=\"Capa 2\" viewBox=\"0 0 47.46 47.46\"><defs><style>      .cls-1 {        fill: #ffc72c;        stroke-width: 0px;      }    <\/style><\/defs><g id=\"PROVEN_EFFICACY\" data-name=\"PROVEN EFFICACY\"><g id=\"ICON_MORE\" data-name=\"ICON MORE\"><path class=\"cls-1\" d=\"M23.73,0C10.64,0,0,10.64,0,23.73s10.64,23.73,23.73,23.73,23.73-10.64,23.73-23.73S36.81,0,23.73,0ZM23.73,44.07c-11.21,0-20.34-9.12-20.34-20.34S12.51,3.39,23.73,3.39s20.34,9.12,20.34,20.34-9.12,20.34-20.34,20.34Z\"><\/path><path class=\"cls-1\" d=\"M33.33,22.03h-7.91v-7.91c0-.94-.76-1.69-1.69-1.69s-1.69.76-1.69,1.69v7.91h-7.91c-.94,0-1.69.76-1.69,1.69s.76,1.69,1.69,1.69h7.91v7.91c0,.94.76,1.69,1.69,1.69s1.69-.76,1.69-1.69v-7.91h7.91c.94,0,1.69-.76,1.69-1.69s-.76-1.69-1.69-1.69Z\"><\/path><\/g><\/g><\/svg>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-be5bc6f\" data-id=\"be5bc6f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fb2ddbf elementor-widget elementor-widget-text-editor\" data-id=\"fb2ddbf\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Progressione e miglioramento della disabilit\u00e0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-208c8db elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"208c8db\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"#analisi\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" id=\"Capa_2\" data-name=\"Capa 2\" viewBox=\"0 0 47.46 47.46\"><defs><style>      .cls-1 {        fill: #ffc72c;        stroke-width: 0px;      }    <\/style><\/defs><g id=\"PROVEN_EFFICACY\" data-name=\"PROVEN EFFICACY\"><g id=\"ICON_MORE\" data-name=\"ICON MORE\"><path class=\"cls-1\" d=\"M23.73,0C10.64,0,0,10.64,0,23.73s10.64,23.73,23.73,23.73,23.73-10.64,23.73-23.73S36.81,0,23.73,0ZM23.73,44.07c-11.21,0-20.34-9.12-20.34-20.34S12.51,3.39,23.73,3.39s20.34,9.12,20.34,20.34-9.12,20.34-20.34,20.34Z\"><\/path><path class=\"cls-1\" d=\"M33.33,22.03h-7.91v-7.91c0-.94-.76-1.69-1.69-1.69s-1.69.76-1.69,1.69v7.91h-7.91c-.94,0-1.69.76-1.69,1.69s.76,1.69,1.69,1.69h7.91v7.91c0,.94.76,1.69,1.69,1.69s1.69-.76,1.69-1.69v-7.91h7.91c.94,0,1.69-.76,1.69-1.69s-.76-1.69-1.69-1.69Z\"><\/path><\/g><\/g><\/svg>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-d820031\" data-id=\"d820031\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a9d9799 elementor-widget elementor-widget-text-editor\" data-id=\"a9d9799\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Aumento della percentuale di pazienti senza evidenza di attivit\u00e0 di malattia (NEDA)<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f711844 elementor-view-default elementor-widget elementor-widget-icon\" data-id=\"f711844\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-icon-wrapper\">\n\t\t\t<a class=\"elementor-icon\" href=\"#aumento\">\n\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" id=\"Capa_2\" data-name=\"Capa 2\" viewBox=\"0 0 47.46 47.46\"><defs><style>      .cls-1 {        fill: #ffc72c;        stroke-width: 0px;      }    <\/style><\/defs><g id=\"PROVEN_EFFICACY\" data-name=\"PROVEN EFFICACY\"><g id=\"ICON_MORE\" data-name=\"ICON MORE\"><path class=\"cls-1\" d=\"M23.73,0C10.64,0,0,10.64,0,23.73s10.64,23.73,23.73,23.73,23.73-10.64,23.73-23.73S36.81,0,23.73,0ZM23.73,44.07c-11.21,0-20.34-9.12-20.34-20.34S12.51,3.39,23.73,3.39s20.34,9.12,20.34,20.34-9.12,20.34-20.34,20.34Z\"><\/path><path class=\"cls-1\" d=\"M33.33,22.03h-7.91v-7.91c0-.94-.76-1.69-1.69-1.69s-1.69.76-1.69,1.69v7.91h-7.91c-.94,0-1.69.76-1.69,1.69s.76,1.69,1.69,1.69h7.91v7.91c0,.94.76,1.69,1.69,1.69s1.69-.76,1.69-1.69v-7.91h7.91c.94,0,1.69-.76,1.69-1.69s-.76-1.69-1.69-1.69Z\"><\/path><\/g><\/g><\/svg>\t\t\t<\/a>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<div class=\"elementor-element elementor-element-d67c38d elementor-widget elementor-widget-menu-anchor\" data-id=\"d67c38d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"riduzione\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8141e63 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8141e63\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ac28bb0\" data-id=\"ac28bb0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-72189a8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"72189a8\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-3efacd0\" data-id=\"3efacd0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-067f22e elementor-widget elementor-widget-heading\" data-id=\"067f22e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Il primo anti-CD20 a raggiungere un ARR &lt;0,1 in 2 studi clinici di fase 3\n<sup>2<\/sup><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e404a69 elementor-widget elementor-widget-heading\" data-id=\"e404a69\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Negli studi clinici di ULTIMATE I e II, BRIUMVI\u00ae ha ridotto significativamente i tassi di ricaduta rispetto a teriflunomide a 96 settimane<sup>4<\/sup><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a003867 elementor-widget elementor-widget-text-editor\" data-id=\"a003867\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Endpoint finale primario:<\/strong> ARR\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-09e77ae elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"09e77ae\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-8645784\" data-id=\"8645784\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4c717f9 elementor-widget elementor-widget-text-editor\" data-id=\"4c717f9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>Meno di 1 ricaduta<\/span> per ogni 12 anni-paziente con BRIUMVI\u00ae nello studio di ULTIMATE I<sup>a,b<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-1e9b74d\" data-id=\"1e9b74d\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-57ce997 elementor-widget elementor-widget-text-editor\" data-id=\"57ce997\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>Meno di 1 ricaduta<\/span> per ogni 11 anni-paziente con BRIUMVI\u00ae nello studio di ULTIMATE II<sup>a,b<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-aad6df3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"aad6df3\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-39cede7\" data-id=\"39cede7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cd3fd68 elementor-widget elementor-widget-image\" data-id=\"cd3fd68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"2560\" height=\"1356\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1.png\" class=\"attachment-full size-full wp-image-28982\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1.png 2560w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-300x159.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-1024x542.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-768x407.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-1536x814.png 1536w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-2048x1085.png 2048w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065008\/briumvi-proven-efficacy-img-1-2-1-scaled-1-600x318.png 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8c9b300 elementor-widget elementor-widget-text-editor\" data-id=\"8c9b300\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<sup>a<\/sup>ARR per BRIUMVI\u00ae osservato negli studi di fase 3 di ULTIMATE I e II. I confronti tra gli studi non sono appropriati a causa della variazione delle popolazioni di pazienti analizzati nei diversi studi.<sup>2<\/sup>\n\n<sup>b<\/sup>Gli anni-paziente sono stati calcolati sulla base degli ARR medi della popolazione mITT (1\/0,08 = 12,5 e 1\/0,09 = 11,1).2\nSulla base della popolazione mITT modificata e post basale.<sup>2<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5465e2d elementor-widget elementor-widget-text-editor\" data-id=\"5465e2d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tUn maggior numero di pazienti liberi da ricadute con BRIUMVI\u00ae nei 2 studi clinici<sup>1<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a0b54ac elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a0b54ac\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b738f8a\" data-id=\"b738f8a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-27cb3ee elementor-widget elementor-widget-image\" data-id=\"27cb3ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1169\" height=\"401\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1.png\" class=\"attachment-full size-full wp-image-28983\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1.png 1169w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1-300x103.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1-1024x351.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1-768x263.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065010\/briumvi-proven-efficacy-img-2-1-600x206.png 600w\" sizes=\"(max-width: 1169px) 100vw, 1169px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2e80cb8\" data-id=\"2e80cb8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-78e806d elementor-widget elementor-widget-image\" data-id=\"78e806d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"1139\" height=\"401\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1.png\" class=\"attachment-full size-full wp-image-28984\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1.png 1139w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1-300x106.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1-1024x361.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1-768x270.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065012\/briumvi-proven-efficacy-img-3-1-600x211.png 600w\" sizes=\"(max-width: 1139px) 100vw, 1139px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-f886165 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f886165\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-82bcedf\" data-id=\"82bcedf\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-026a311 elementor-widget elementor-widget-heading\" data-id=\"026a311\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Percentuale di pazienti liberi da ricadute a 96 settimane.<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-96131dd elementor-widget elementor-widget-menu-anchor\" data-id=\"96131dd\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"soppressione\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-9964575 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9964575\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-61b7d1a\" data-id=\"61b7d1a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a4447bc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a4447bc\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-5ccd8c2\" data-id=\"5ccd8c2\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5585933 elementor-widget elementor-widget-heading\" data-id=\"5585933\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">BRIUMVI\u00ae ha mostrato una soppressione  delle lesioni T1Gd+ rispetto alla teriflunomide<sup>1,2<\/sup><\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-de548bc elementor-widget elementor-widget-text-editor\" data-id=\"de548bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tLe lesioni T1 Gd+ sono state soppresse del 97% rispetto a teriflunomide\u00a0<sup>1,2<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-44aaa17 elementor-widget elementor-widget-text-editor\" data-id=\"44aaa17\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Endpoint finale secondario: lesioni T1 Gd+ alla settimana 96<\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a16ccc7 elementor-widget elementor-widget-image\" data-id=\"a16ccc7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1468\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1.png\" class=\"attachment-full size-full wp-image-28985\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1.png 2560w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-300x172.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-1024x587.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-768x440.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-1536x881.png 1536w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-2048x1174.png 2048w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065022\/briumvi-proven-efficacy-img-13-v2-12-2-1-scaled-1-600x344.png 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-711de1e elementor-widget elementor-widget-text-editor\" data-id=\"711de1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tBasato sulla popolazione MRI-mITT (pazienti mITT che hanno una risonanza magnetica basale e post basale).\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4989e0f elementor-widget elementor-widget-text-editor\" data-id=\"4989e0f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tLa soppressione delle lesioni T2 nuove o in espansione \u00e8 stata del 92% in ULTIMATE I e del 90% in ULTIMATE II rispetto a teriflunomide<sup>1,2<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-fd79d4a elementor-widget elementor-widget-text-editor\" data-id=\"fd79d4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Endpoint secondario: lesioni T2 nuove o in aumento alla settimana 96<\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ffb0016 elementor-widget elementor-widget-image\" data-id=\"ffb0016\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1533\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1.png\" class=\"attachment-full size-full wp-image-28986\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1.png 2560w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-300x180.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-1024x613.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-768x460.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-1536x920.png 1536w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-2048x1226.png 2048w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065032\/briumvi-proven-efficacy-img-5-2-1-scaled-1-600x359.png 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-842a8af elementor-widget elementor-widget-text-editor\" data-id=\"842a8af\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tBasato sulla popolazione MRI-mITT (pazienti mITT che hanno una risonanza magnetica basale e post basale).\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6a6b702 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6a6b702\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-35fbfb6\" data-id=\"35fbfb6\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-5c4f052 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5c4f052\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-c7e21f4\" data-id=\"c7e21f4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3841a3a elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-heading\" data-id=\"3841a3a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Gli studi ULTIMATE I e II hanno evidenziato la progressione della disabilit\u00e0 nei pazienti a 12 settimane <sup>1,2<\/sup>\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-08ba06a elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"08ba06a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tIl 95% dei pazienti negli studi ULTIMATE I e II non ha avuto una progressione confermata della disabilit\u00e0 (CDP) a 12 settimane e >95% dei pazienti non ha avuto una CDP a 24 settimane 1,2\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8e812c7 elementor-widget elementor-widget-menu-anchor\" data-id=\"8e812c7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"analisi\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da170b5 elementor-widget elementor-widget-text-editor\" data-id=\"da170b5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Analisi combinata predefinita:<\/strong> CDP\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2a5d76c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2a5d76c\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-b904155\" data-id=\"b904155\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e6f773 elementor-widget elementor-widget-image\" data-id=\"7e6f773\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1261\" height=\"1045\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1.png\" class=\"attachment-full size-full wp-image-28987\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1.png 1261w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1-300x249.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1-1024x849.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1-768x636.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065036\/briumvi-proven-efficacy-img-6-2-1-600x497.png 600w\" sizes=\"(max-width: 1261px) 100vw, 1261px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-20386f7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"20386f7\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-bf1acb4\" data-id=\"bf1acb4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-89f9632 elementor-widget elementor-widget-text-editor\" data-id=\"89f9632\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Sulla base delle stime di Kaplan-Meier e della popolazione mITT.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-91d7526 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"91d7526\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">La CDP a 12 settimane tra i 2 gruppi di trattamento non ha raggiunto la significativit\u00e0 statistica.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">La CDP a 24 settimane non \u00e8 stata formalmente testata per la significativit\u00e0.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">La progressione della malattia \u00e8 stata misurata mediante EDSS e definita come un aumento di \u22651,0 punti rispetto al punteggio EDSS basale se il punteggio basale era \u22645,5, o un aumento di \u22650,5 punti se il punteggio basale era &gt;5,5.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-030aa3f elementor-widget elementor-widget-heading\" data-id=\"030aa3f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Gli studi di ULTIMATE I e II hanno evidenziato il miglioramento della disabilit\u00e0 nei pazienti<sup>2<\/sup> <\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3833a48 elementor-widget elementor-widget-heading\" data-id=\"3833a48\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<p class=\"elementor-heading-title elementor-size-default\">Il 12% dei pazienti che hanno ricevuto BRIUMVI\u00ae ha ottenuto un miglioramento confermato della disabilit\u00e0 (CDI) a 12 settimane e il 9,6% ha ottenuto un CDI a 24 settimane, misurato<sup>2<\/sup> dall'EDSS.<sup>2<\/sup>\n\n<\/p>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cfef61c elementor-widget elementor-widget-text-editor\" data-id=\"cfef61c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Analisi combinata predefinita terziaria:<\/strong> CDI\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-201d5ee elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"201d5ee\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f2a17f3\" data-id=\"f2a17f3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-887ca89 elementor-widget elementor-widget-image\" data-id=\"887ca89\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1250\" height=\"1042\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1.png\" class=\"attachment-full size-full wp-image-28988\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1.png 1250w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1-300x250.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1-1024x854.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1-768x640.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065039\/briumvi-proven-efficacy-img-8-2-1-600x500.png 600w\" sizes=\"(max-width: 1250px) 100vw, 1250px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3c8b0cc\" data-id=\"3c8b0cc\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-802d635 elementor-widget elementor-widget-image\" data-id=\"802d635\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1243\" height=\"1040\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1.png\" class=\"attachment-full size-full wp-image-28989\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1.png 1243w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1-300x251.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1-1024x857.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1-768x643.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065043\/briumvi-proven-efficacy-img-9-2-1-600x502.png 600w\" sizes=\"(max-width: 1243px) 100vw, 1243px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-ad86ed1 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ad86ed1\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-480bfb4\" data-id=\"480bfb4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-56921b8 elementor-widget elementor-widget-text-editor\" data-id=\"56921b8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Sulla base delle stime di Kaplan-Meier e della popolazione mITT.<\/p><p>\u00a0<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-761dc19 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"761dc19\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Il miglioramento della disabilit\u00e0 \u00e8 stato misurato in base all'EDSS e definito come una riduzione di \u22651,0 punti rispetto al punteggio EDSS basale, o una riduzione di \u22650,5 punti se il punteggio EDSS basale era &gt;5,5.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">La CDI a 12 e 24 settimane non \u00e8 stata formalmente testata per la significativit\u00e0.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8ea2f10 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8ea2f10\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-b2a4b11\" data-id=\"b2a4b11\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-0e771b5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0e771b5\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-e7a866a\" data-id=\"e7a866a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c88c059 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"c88c059\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tQuasi la met\u00e0 (45%) dei pazienti ha raggiunto il NEDA (nessuna evidenza di attivit\u00e0 della malattia) con BRIUMVI\u00ae negli studi ULTIMATE I e II<sup>5<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-43fff43 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"43fff43\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-759b360\" data-id=\"759b360\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f40f0a1 elementor-widget elementor-widget-text-editor\" data-id=\"f40f0a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Analisi combinata successiva di ULTIMATE I e II:\n<\/strong>\npercentuale di pazienti con NEDA alla settimana 96\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da06f1a elementor-widget elementor-widget-text-editor\" data-id=\"da06f1a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>NEDA-3<\/strong> (settimane 0-96)<sup>5<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-69b9bd0 elementor-widget elementor-widget-image\" data-id=\"69b9bd0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"1309\" height=\"417\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2.png\" class=\"attachment-full size-full wp-image-28990\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2.png 1309w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2-300x96.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2-1024x326.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2-768x245.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065045\/briumvi-proven-efficacy-img-10-2-600x191.png 600w\" sizes=\"(max-width: 1309px) 100vw, 1309px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c7bc262\" data-id=\"c7bc262\" data-element_type=\"column\" data-e-type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-becfa93 elementor-widget elementor-widget-text-editor\" data-id=\"becfa93\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tInformazioni su NEDA-32\nNEDA-3 \u00e8 una valutazione composita definita come pazienti con:\n<ul>\n \t<li>Nessuna ricaduta confermata\n<\/li>\n \t<li>Nessun CDP a 12 settimane\n<\/li>\n \t<li>Nessuna attivit\u00e0 lesionale rilevata tramite risonanza magnetica<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a0a629b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a0a629b\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-3091306\" data-id=\"3091306\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e80b62d elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-text-editor\" data-id=\"e80b62d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\tPercentuale di pazienti trattati con BRIUMVI\u00ae che raggiungono le misure dei singoli componenti del NEDA-3<sup>5<\/sup>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2d8904f elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2d8904f\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-3798ffe\" data-id=\"3798ffe\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4703226 elementor-widget elementor-widget-text-editor\" data-id=\"4703226\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>86.5%<\/span><br>\nNessuna ricaduta confermata\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-caab557\" data-id=\"caab557\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ee3dc6d elementor-widget elementor-widget-text-editor\" data-id=\"ee3dc6d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>94.0%<\/span><br>\nNessuna lesione Gd+ T1\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-7359a73\" data-id=\"7359a73\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b30c3d6 elementor-widget elementor-widget-text-editor\" data-id=\"b30c3d6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>55.2%<\/span><br>\nNessuna lesione T2 nuova\/in aumento\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-25 elementor-inner-column elementor-element elementor-element-06f3ab7\" data-id=\"06f3ab7\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-de3ad8d elementor-widget elementor-widget-text-editor\" data-id=\"de3ad8d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<span>94.6%<\/span><br>\nNessuna CDP a 12 settimane\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c907902 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c907902\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-edec340\" data-id=\"edec340\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2b64af9 elementor-widget elementor-widget-text-editor\" data-id=\"2b64af9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Le raccomandazioni di consenso MAGNIMS-CMSC-NAIMS del 2021 sull&#8217;uso della risonanza magnetica nei pazienti con SM raccomandano di ottenere una nuova risonanza magnetica cerebrale di base, di solito a 3-6 mesi dall&#8217;inizio del trattamento, per evitare un&#8217;interpretazione errata delle lesioni sviluppatesi prima dell&#8217;inizio della terapia..<sup>6,7<\/sup><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-83c8de8 elementor-widget elementor-widget-menu-anchor\" data-id=\"83c8de8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"menu-anchor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-menu-anchor\" id=\"aumento\"><\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-30dc304 elementor-widget elementor-widget-text-editor\" data-id=\"30dc304\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<strong>Aumento della percentuale di pazienti senza evidenza di attivita&#8217; di malattia (NEDA)<\/strong>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14db14f elementor-widget elementor-widget-image\" data-id=\"14db14f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"2273\" src=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1.png\" class=\"attachment-full size-full wp-image-28991\" alt=\"\" srcset=\"https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1.png 2560w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-300x266.png 300w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-1024x909.png 1024w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-768x682.png 768w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-1536x1364.png 1536w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-2048x1818.png 2048w, https:\/\/static.neuraxpharm.com\/wp-content\/uploads\/sites\/5\/2026\/05\/06065059\/briumvi-proven-efficacy-img-13-v2-2-scaled-1-600x533.png 600w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0ffa094 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0ffa094\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[],&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-08544d5\" data-id=\"08544d5\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-230a704 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"230a704\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-616f43e\" data-id=\"616f43e\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fcc07b7 elementor-align-center elementor-widget elementor-widget-button\" data-id=\"fcc07b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"button.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-button-wrapper\">\n\t\t\t\t\t<a class=\"elementor-button elementor-button-link elementor-size-sm\" href=\"https:\/\/8574878.fs1.hubspotusercontent-na1.net\/hubfs\/8574878\/BRIUMVI\/2026\/SMPC\/RIASSUNTO%20Briumvi%20September3rd2025%20COLOR_Print%20pages.pdf\">\n\t\t\t\t\t\t<span class=\"elementor-button-content-wrapper\">\n\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Consulta il riassunto delle caratteristiche del prodotto<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Home BRIUMVI\u00ae is where efficacy meets efficiency for patients with relapsing MS Riduzione significativa delle ricadute (endpoint primario) Soppressione quasi completa delle lesioni Progressione e miglioramento della disabilit\u00e0 Aumento della percentuale di pazienti senza evidenza di attivit\u00e0 di malattia (NEDA) Il primo anti-CD20 a raggiungere un ARR &lt;0,1 in 2 studi clinici di fase 3 [&hellip;]<\/p>\n","protected":false},"author":2493,"featured_media":0,"parent":27270,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-27307","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.2 (Yoast SEO v27.5) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Sclerosi Multipla: Efficacia Provata - Neuraxpharm Italia<\/title>\n<meta name=\"description\" content=\"Scopri l&#039;efficacia provata di BRIUMVI\u00ae nella sclerosi multipla: riduzione significativa delle ricadute e soppressione delle lesioni. 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